In pollution-free aquaculture, fishery drugs should be used regularly to prevent aquaculture plant and animal diseases. The efficacy of fishery drugs will directly affect the aquaculture costs and aquaculture benefits. In order to ensure the effective use of fishery drugs in aquaculture production, the author will summarize many factors affecting the efficacy of fishery drugs as follows for reference by farmers. First, the drug dose, dosage form The effect of the drug varies with the size of the dose, and even a qualitative change occurs. For example, when the zinc astringent zinc sulfate is used locally, the low concentration has astringent effect, the medium concentration has a stimulatory effect, and the high concentration has a corrosive effect. . The dosage form of the drug is different, and even if the drug dosage is the same, the time of action, effect and effect are different. Second, the mode of administration The route of administration, time of administration, frequency of administration, and repeated use of the drug can all affect the effects of the drug. The external route of administration such as drug bath (or over-spray) and the oral (or injection) route of administration have obvious differences in the effects of the drugs; different administration times (day or night), even if the dose of the drug is used The same, the effect will be different. Third, animal status Aquatic animals' own conditions and physiological conditions will produce different pharmacodynamic effects. 1. Species differences: There are differences in the sensitivity of drugs between different species, aquatic animals or different individuals in the same line. 2. Physiological differences: Generally young and old aquatic animals are more sensitive to drugs. 3. Individual differences: Different individuals have different drug tolerances, which may be related to the individual's genetic factors. 4. Functional and pathological conditions of the body: Aquatic animals that are generally emaciated, malnourished, and under pathological conditions are more sensitive to drugs. Fourth, environmental factors For aquatic animals, the impact of the environment on the effects of drugs is greater, the main influencing factors: 1. Water temperature: Drugs are generally positively related to water temperature, but some drugs are the opposite. 2. Organics: It will affect the efficacy of most drugs, such as potassium permanganate, chlorine disinfectants. 3. pH: Antibacterial agents such as acidic drugs, anionic surfactants, and tetracyclines are weakened in alkaline water; alkaline drugs, sulfa drugs, and cationic surfactants, etc., increase in potency with increasing pH. 4. Dissolved oxygen: When the dissolved oxygen is high, the tolerance of the aquatic animal to the drug is enhanced; when the dissolved oxygen is low, the aquatic animal is prone to poisoning. 5. Light and Season: Aquatic animals are more tolerant of drugs at night than during the day and more sensitive to drugs during the summer than in the winter. 6. Pathogen status and resistance: Some parasites that form cysts can often form cysts under the stimulation of drugs and their resistance to drugs is significantly enhanced. In addition, stress factors such as fishing, transport, and water exchange can also increase the sensitivity of aquatic animals to drugs. Pet Harness,Harness Chain,Harness Dog Adjustable,Customizable Dog Harness YIWU CHUANGCHENG IMPORT&EXPORT CO.,LTD , https://www.tradingsix.com