Pharmaceutical Powder Isoprenaline Hydrochloride for Bronchial Asthma

October 22, 2018

  • Model NO.: 51-30-9
  • Customized: Non-Customized
  • Suitable for: Adult
  • Purity: >99%
  • Mf: C11h18clno3
  • Einecs: 200-089-8
  • Melting Point: 165-175 °c (DEC.)(Lit.)
  • Usage: Used in The Treatment of Bradycardia; Bronchodilat
  • Trademark: Saichuang
  • Specification: Enterprise standard
  • Powder: Yes
  • Certification: HSE, ISO 9001
  • State: Solid
  • CAS: 51-30-9
  • MW: 247.72
  • Appearance: White Crystalline Powder
  • Grade: Pharma Grade
  • MOQ: 10g
  • Transport Package: Discreet Package
  • Origin: China
Pharmaceutical Adrenoceptor Isoprenaline Hydrochloride For Bronchial Asthma


Isoprenaline Hydrochloride Quick Detail
Product Name
Isoprenaline Hydrochloride
 
Synonym
2-benzenediol,4-(1-hydroxy-2-((1-methylethyl)amino)ethyl)-hydrochloride;3,4-dihydroxy-alpha-((isopropylamino)methyl)-benzylalcohohydrochloride;alpha-(isopropylaminomethyl)-3, 4-dihydroxybenzylalcoholhydrochloride; euspiran; isadrine; isoprenalinechloride; isopropylnorepinephrine-hydrochloride; isoproterenolmonohydrochloride
 
CAS
51-30-9
 
MF
C11H18ClNO3
 
MW
247.72
 
EINECS
200-089-8
 
Purity
99%
 
Appearance
White crystalline powder
 
Melting Point
165-175 °C (dec.)(lit.)
 
Grade
Pharma Grade
 
Usage
Isoproterenol is a non-selective beta-adrenergic agonist. Isoproterenol is used in the treatment of bradycardia; bronchodilator.
 


Description

Isoprenaline (INN) or isoproterenol (USAN, trade names Medihaler-Iso and Isuprel) is a medication used for the treatment of bradycardia (slow heart rate), heart block, and rarely for asthma. It is a non-selective beta-adrenergic agonist and structurally similar to adrenaline.

Isoproterenol hydrochloride is a phenethylamine derivative and selective β-AR adrenergic agonist shown to
increase cytosolic cAMP. Isoproterenol hydrochloride exhibits promotion of glycogen breakdown and causes bronchodilation and vasorelaxant effects. Also potentially stimulates relaxation in nitric oxide mediated endothelium-dependent smooth muscle. Isoproterenol Hydrochloride is an activator of β2-AR and ERK.

Isoprenaline hydrochloride is also known as isoproterenol hydrochloride.The active ingredient is the chemical in a medicine that makes it work. Medicines can have more than one active ingredient and be available under different brand names. Medicines include both active ingredients and inactive ingredients.


COA
Items Standards
Results
 
Appearance White or almost white crystalline powder
white crystalline powder
 

Melting point
   		165 to 170 .
168 ~169 
 
0.2 (310 nm)
0.02
 
Sulfid 2000 ppm
conforms
 
Loss on drying 1.0 %
0.01%
 
Ignition residue 0.2 %
0.02%
 
Chloride 13.9% 14.6%
14.4%
 

Assay
 		 97.0% 101.5 %
100.4 %
 
<3000 ppm
100 ppm
 
<5000 ppm
60ppm
 
Conclusion
USP31
 



Application

Isoprenaline hydrochloride (51-30-9) is a sympathomimetic beta adrenergic agonist medication. It is structurally similar to epinephrine (adrenaline) but acts selectively on beta receptors, activating β1 and β2 receptors equally.

Its primary use is for bradycardia or heart block. By activating β1-receptors on the heart, it induces positive chronotropic, dromotropic, and inotropic effects.and it can be used as an inhaled aerosol to treat asthma, although this is currently a rare treatment. Although it activates all beta adrenergic receptors, it works in a similar fashion to the more selective β2-adrenergic agonists e.g. salbutamol, by relaxing the airways to increase airflow.

It is also supplied in ampules under the brand name Isuprel for injection and in sublingual pill form for treatment of asthma, chronic bronchitis and emphysema.


Usage

1) Bronchial asthma: Application to control acute asthma attacks, usually inhaled administration, the role of fast and strong, but short duration.

2) Heart stops together: For the treatment of various reasons, drowning, electric shock, surgery and other accidents and poisoning caused by cardiac arrest. Necessary, with epinephrine and norepinephrine with Wu.

3) Atrioventricular block.

4) Anti-shock: Cardiogenic shock, and can be used in septic shock. On the high central venous pressure, cardiac output is the lower, should be the basis of their blood volume and then using this product.


Advantage

1, High quality with competitive price
1) Standard: Enterprise Standard
2) All Purity ≥99%
3) We are manufacturer and can provide high quality products with factory price. 

2, Fast and safe delivery
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

3, We have clients throughout the world
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality,competitive price,fast delivery ,first-class service gain the trust and praise from the customers.
 

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